AI Guide for R&D Excellence in Pharma

The Decision Desk · R&D Excellence Guide · AI in Pharma · September 2026 Edition
Eleven Decisions

The AI Impact Guidefor R&D Excellence Leaders.

Most R&D AI roadmaps fund the exciting use case first and the highest-leverage one last. This guide gives you the right order, a ranked, sourced priority sequence across Discovery and Clinical Development, with the dollar, time, and probability-of-success impact behind each.

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What's inside the guide
01Strategy: what should R&D AI actually optimise for?
02Sequencing: how should we sequence R&D AI investment?
03Discovery & preclinical: where should these teams start?
04Clinical development: where should these teams start?
05Data foundation: what does R&D AI require?
06Build, buy, partner: what goes where?
07Governance: how should it differ by risk tier?
08Operating model: centralised or federated?
09People: what happens as AI scales?
10Upskilling: how do we adopt without stalling?
11Compounding value: how do we know it's working?
R&D Excellence Guide to AI in Pharma, book mockup
Two sequencing lenses When to fund a use case, by lever and proof speed, and whether it has earned funding at all, by opportunity and capture readiness.
A ranked, sourced priority list Separate final sequences for Discovery & Preclinical and Clinical Development, with speed, probability-of-success and cost impact cited to named research.
A 12-month agenda Plus the target R&D AI stack, one connected brain instead of ten point tools, with a role-by-role change plan.

Traditional drug development costs $2.6 to 2.8B and takes 10 to 15 years per approved drug, with failure rates exceeding 90%.

Industry drug-development research, 2026 · cited in the guide

Part of a 5-week series · Week 4 of 5

This is Week 4 of DecisionX's September series on Decision AI in Pharma, covering the CEO agenda, the CDO/CAIO architecture, Commercial Excellence, this R&D Excellence guide, and Manufacturing Excellence, closing with a case study on what this actually returns.

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R&D Excellence Guide to AI in Pharma
The Decision Desk · R&D Excellence Guide

R&D Excellence Guide for AI in Pharma

Eleven questions. Two functions. One sourced sequence. Free, no spam, no sales pitch first.

Backed by peer-reviewed research and FDA guidance

The Decision Desk

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